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Index > Protein center > LPL(Gene name) > Bovine
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  • LPL (Gene name),
  • Lipoprotein lipase (Protein name ),  LIPL_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LPL;
    Protein name:
    Lipoprotein lipase(LPL);
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer (By similarity). Interacts with APOC2; the interaction activates LPL activity in the presence of lipids. Interacts with GPIHBP1.
    Function:
    The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor Secreted Locates to the plasma membrane of microvilli of hepatocytes with triacyl-glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles.
    Protein Attributes:
    Sequence length:
    478
    Sequence:
    50:
    MESKALLLLA | LSVCLQSLTV | SRGGLVAADR | ITGGKDFRDI | ESKFALRTPE | 
    100:
    DTAEDTCHLI | PGVTESVANC | HFNHSSKTFV | VIHGWTVTGM | YESWVPKLVA | 
    150:
    ALYKREPDSN | VIVVDWLSRA | QQHYPVSAGY | TKLVGQDVAK | FMNWMADEFN | 
    200:
    YPLGNVHLLG | YSLGAHAAGI | AGSLTNKKVN | RITGLDPAGP | NFEYAEAPSR | 
    250:
    LSPDDADFVD | VLHTFTRGSP | GRSIGIQKPV | GHVDIYPNGG | TFQPGCNIGE | 
    300:
    ALRVIAERGL | GDVDQLVKCS | HERSVHLFID | SLLNEENPSK | AYRCNSKEAF | 
    350:
    EKGLCLSCRK | NRCNNMGYEI | NKVRAKRSSK | MYLKTRSQMP | YKVFHYQVKI | 
    400:
    HFSGTESNTY | TNQAFEISLY | GTVAESENIP | FTLPEVSTNK | TYSFLLYTEV | 
    450:
    DIGELLMLKL | KWISDSYFSW | SNWWSSPGFD | IGKIRVKAGE | TQKKVIFCSR | 
    478:
    EKMSYLQKGK | SPVIFVKCHD | KSLNRKSG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine LPL
    Cat.:
    E0386h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine LPL
    Cat.:
    E0386r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine LPL
    Cat.:
    E0386p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine LPL
    Cat.:
    E0386m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine LPL
    Cat.:
    E0386b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine LPL
    Cat.:
    E0386c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine LPL
    Cat.:
    U0386m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine LPL
    Cat.:
    U0386p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine LPL
    Cat.:
    U0386r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine LPL
    Cat.:
    U0386b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine LPL
    Cat.:
    U0386h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine LPL
    Cat.:
    U0386c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine LPL
    Cat.:
    P0386Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine LPL
    Polyclonal Antibody for Bovine LPL
    Polyclonal Antibody for Bovine LPL
    Polyclonal Antibody for Bovine LPL
    Cat.:
    P0386Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine LPL
    Cat.:
    P0386Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine LPL
    Monoclonal Antibody for Bovine LPL
    Monoclonal Antibody for Bovine LPL
    Monoclonal Antibody for Bovine LPL
    Monoclonal Antibody for Bovine LPL
    Monoclonal Antibody for Bovine LPL
    Protein for Bovine LPL
    Protein for Bovine LPL
    Protein for Bovine LPL
    Protein for Bovine LPL
    Protein for Bovine LPL
    Protein for Bovine LPL

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Uterus.
    2. 2.
      "Molecular cloning and sequence of a cDNA coding for bovine lipoprotein lipase."
      Senda M. , Oka K. , Brown W.V. , Qasba P.K. , Furuichi Y.
      Proc. Natl. Acad. Sci. U.S.A.84:4369-4373(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 29-478
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-478;DISULFIDE BONDS
      tissue: Mammary gland.
    4. 4.
      "Lipoprotein lipases from cow, guinea-pig and man. Structural characterization and identification of protease-sensitive internal regions."
      Bengtsson-Olivecrona G. , Olivecrona T. , Joernvall H.
      Eur. J. Biochem.161:281-288(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-55
    5. 5.
      "Metabolism of endothelial cell-bound lipoprotein lipase. Evidence for heparan sulfate proteoglycan-mediated internalization and recycling."
      Saxena U. , Klein M.G. , Goldberg I.J.
      J. Biol. Chem.265:12880-12886(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HEPARIN BINDING;SUBCELLULAR LOCATION
    6. 6.
      "Binding and intracellular trafficking of lipoprotein lipase and triacylglycerol-rich lipoproteins by liver cells."
      Casaroli-Marano R.P. , Garcia R. , Vilella E. , Olivecrona G. , Reina M. , Vilaro S.
      J. Lipid Res.39:789-806(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding."
      MacPhee C.E. , Hatters D.M. , Sawyer W.H. , Howlett G.J.
      Biochemistry39:3433-3440(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH APOC2;ENZYME ACTIVITY
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